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How a Desert Lizard Helped Create Today's GLP 1 Drugs NewBeauty Glucagon like peptide 1 in health and disease Nature Reviews Endocrinology Reflections on the discovery GLP 1 as a satiety hormone: Implications for obesity therapy and future directions European Journal of Clinical Nutrition youtheory & Weight Loss Expert Launch Doctor Formulated GLP 1 Support Youtheory For years, researchers have known that obesity is associated with an increased risk of developing and dying from several cancers, including breast cancer. At ASCO 2026, new studies examining GLP 1 receptor agonists
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Best in 7 days
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Best in 7 days
4.3 ★★★★★
Based on 2472 reviews
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Product Reviews
★★★★★ 5
This is actually a fantastic dog toy!
Color: Large size (ø 7.4")
I originally got this for my golden retriever. He loves all things ball-shaped and I figured the handles would make this really easy for him to carry and for me to tug. It was a fantastic hit not only with the retriever but my lab and even my older Great Dane also love this toy. It's about the size of a soccer ball and covered in a nice rubber that can be chewed off if you have a destructive player but is more than durable enough for tossing around the house or even in the yard. Chewability-wise, The Dane managed to chew a couple of chunks off the handle part but he's probably a pretty extreme example. I think this would hold up just fine for most dogs' play. I just have to supervise it with my Dane so that he doesn't chew it into a pile of rubber.
The biggest surprise of this ball was the fact that it has one of those slide whistles in it that makes a noise as it tumbles and rolls around. This proved irresistible to the Golden Retriever and the Lab. Every time they hear the slide whistle inside, they get up from wherever they are and focus 100% on this ball.
It has some heft to it and it bounces a little but not as much as a regular ball its size, it's fun for the little ones to play with inside but it's primarily an outdoor dog toy. The handles are big enough for a human hand to hold them comfortably. It rolls in a hard-to-predict way that is extra helpful for the smaller dogs to chase.
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Reviewed in the United States on December 22, 2025
★★★★★ 1
Trash
Color: Medium size (ø 5.5")
Poor quality,’trash
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Reviewed in the United States on January 9, 2026
★★★★★ 5
Aggressive chewers have met their match.
Size: 10.5 inch Rubber Flex Tread
We purchased this toy in 2022, it finally broke last night. Four years of rough play with 2 boxers who are aggressive chewers. They would tug together, gnaw on it for hours, and often leave it outside exposed to the elements, but this toy just kept going. It was by far their favorite toy, it kept them busy for hours. I just ordered a replacement. Well worth the money, perfect size. Highly recommend.
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Reviewed in the United States on April 1, 2026
★★★★★ 5
Durable, fun, and safe for my dog
Size: 10.5 inch Rubber Flex Tread
I have a 10 month old, 50 lb mutt who has the musculature of a pit bull and the muzzle of a GSD. Buttercup’s favorite past-time is shredding toys into teeny tiny bits, but sometimes those bits don’t come back out of her mouth. She can’t have tennis balls, stuffies, anything with a squeaker, silicone toys, plastic toys, rubber toys with spikes or small appendages, anything with rope, or most chews & bones. She chewed her first and only $8+ XL bully stick like a corn chip. Finding indoor enrichment is a challenge. Buttercup is extremely pleased with this tire tug thingy, it is very ergonomic for both her and me to get a handle on it, it has more movement than any other toy she can safely have, and it’s very durable. After more than a week, there’s only a little bit of tread missing, which is definitely the best-case outcome with a super chewer. I think this is a good alternative to GoNut toys because it’s solid & dense while also a little bit easier & more interesting to play with, and very unlike GoNuts, this Tonka toy is very reasonably priced. I also think this it’s a good size for almost any breed of dog—I could definitely picture a little Boston or Frenchie dangling from one end. Highly recommended!
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Reviewed in the United States on December 20, 2024
★★★★★ 5
Dog loves it
Size: 10.5 inch Rubber Flex Tread
I would buy this again and again. It’s extremely durable and has held up great with my 9 month old Saint Bernard puppy. We even call it his “pacifier” because every night he grabs it and chews on it until he falls asleep. Definitely a favorite in our house!
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Reviewed in the United States on March 20, 2026
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