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The fear around GLP 1 medicines and muscle loss has been loud. The data, it turns out, is far more reassuring. A new study published in Cell Reports Medicine is the first to GLP 1s & Beyond: Understanding Incretin Mimetic Opportunities Blue Matter Consulting Sulfur burps in patients on GLP 1 therapies may be more than a minor side effect. Experts note these symptoms can reflect underlying gastrointestinal changes linked to the drugs' mechanism of action. While Novo Nordisk's Tresiba snags label boost that could sharpen its safety edge Fierce Pharma 7 Tresiba Side Effects (and How to Manage Them) GoodRx
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Best in 7 days
Best in 7 days
Best in 7 days
Best in 7 days
4.5 ★★★★★
Based on 1183 reviews
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Product Reviews
★★★★★ 1
Toy Not Safe For Chewers
Size: Medium 8", Style: Rubber Dog Toy, Size: Medium 8", Style: Rubber Dog Toy
We bought this tire toy for our puppy for Christmas. It was advertised as a natural rubber dog toy and implied to be durable. It lasted less than two hours.
Our puppy was able to chew off small pieces of the rubber and swallowed some of the bits, which made her extremely sick. She ended up vomiting after ingesting pieces of this toy. I would not recommend this toy, it is not safe especially for dogs that like to chew.
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Reviewed in the United States on January 14, 2026
★★★★★ 5
Definitely recommend for large breed heavy chewing dogs
Size: Large 10", Style: Rubber Dog Toy
Great for a large breed dog. I got the 10inch for my large breed dog. Best choice ever.
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Reviewed in the United States on May 26, 2026
★★★★★ 4
Nice big tire toy
Size: Large 10", Style: Rubber Dog Toy
Our dog has had a tire toy about the same size as this one for 2 years, but it's finally been worn down from his love and zest for it along with weather. When I saw this one, I got excited! Great size for our 80lb 3yo pittie and pretty tough too, although, it's beginning to show signs of wear in only 3 weeks of him playing with it. It's not nearly as rugged as his old rubber tire. We'll have to see how long it actually lasts before I say the price was worth it or not.
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Reviewed in the United States on October 8, 2023
★★★★★ 5
Great dog toy for large breeds!
Size: Large 10", Style: Rubber Dog Toy, Size: Large 10", Style: Rubber Dog Toy
My dog Judge is a 110-pound German Shepherd that loves this tire! It is not the traditional ball that dogs like to play with, but it is so much safer since larger breeds might choke on a ball, as it’s easier to swallow! Judge doesn't go anywhere without his tire! From an owner's standpoint, it’s great also since it’s easy to throw and roll as well as last longer than most toys since it’s made of thick rubber! Best toy for the money I have found by far! Judge has the size large 10”!
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Reviewed in the United States on February 26, 2026
★★★★★ 3
Durable toy
Size: Medium 8", Style: Rubber Dog Toy
This is way too big for my dog. I thought it would be smaller when I ordered it.
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Reviewed in the United States on February 22, 2026
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